I was fortunate enough to work for Dr Bredesen some years ago and was struck by his willingness to consider the complexity of neurodegenerative diseases, in contrast to most researchers who fixate on single-cause perspectives. His multi-faceted approach to minimizing risk factors and taking steps that may potentially ameliorate some aspects of neurodegeneration seems rational and is backed by some data. There are not, however, "multiple studies" that "show Alzheimers can be reversed." One of the reasons for the sparsity of data is that funding bodies such as the NIH remain fixated on single-cause approaches and on mouse model studies, despite the fact that historically mouse model studies fail to translate into human outcomes more than 80% of the time.

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